Ion channels: Doing hard chemistry with hard ions

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Abstract

For years, the mechanisms and structural underpinnings of ion selectivity by ion channel proteins have been inferred by indirect experiments. The recently determined structure of a K+ channel has put flesh on these bones, revealing the coordination chemistry responsible for the unusual combination of high selectivity and high transport rates in ion channels.

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Miller, C. (2000, April 1). Ion channels: Doing hard chemistry with hard ions. Current Opinion in Chemical Biology. Current Biology Ltd. https://doi.org/10.1016/S1367-5931(99)00068-X

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