Isolation and transmission of human retrovirus (human t-cell leukemia virus)

  • Popovic M
  • Sarin P
  • Robert-Gurroff M
 et al. 
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Abstract

Nine new isolates of human T-cell leukemia-lymphoma virus (HTLV) were obtained from cells of seven patients with malignancies of mature T cells and from two clinically normal relatives of a T-cell leukemia patient. These people were from the United States, Israel, the West Indies, and Japan. The virus was detected in the fresh T cells and was isolated from the established T-cell lines. Each isolate is closely related to the first HTLV isolate, and all the new HTLV isolates were transmitted into normal human T cells obtained from the umbilical cord blood of newborns.

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Authors

  • M Popovic

  • P. Sarin

  • M Robert-Gurroff

  • V. Kalyanaraman

  • D Mann

  • J Minowada

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