Key stages of mammary gland development: molecular mechanisms involved in the formation of the embryonic mammary gland.

  • Hens J
  • Wysolmerski J
  • 83

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Abstract

The development of the embryonic mammary gland involves communication between the epidermis and mesenchyme and is coordinated temporally and spatially by various signaling pathways. Although many more genes are likely to control mammary gland development, functional roles have been identified for Wnt, fibroblast growth factor, and parathyroid hormone-related protein signaling. This review describes what is known about the molecular mechanisms that regulate embryonic mammary gland development.

Author-supplied keywords

  • Animals
  • Breast
  • Breast: embryology
  • Breast: growth & development
  • Embryonic Development
  • Epidermis
  • Epidermis: cytology
  • Epidermis: physiology
  • Female
  • Humans
  • Mammary Glands, Animal
  • Mammary Glands, Animal: embryology
  • Mammary Glands, Animal: growth & development
  • Mesoderm
  • Mesoderm: cytology
  • Mesoderm: physiology
  • Mice
  • Milk
  • Milk: secretion
  • Morphogenesis
  • Parathyroid Hormone-Related Protein
  • Parathyroid Hormone-Related Protein: physiology

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Authors

  • Julie R Hens

  • John J Wysolmerski

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