Kinematic improvement following Botulinum Toxin-A injection in upper-limb spasticity due to stroke

  • Fridman E
  • Crespo M
  • Argüello S
 et al. 
  • 28

    Readers

    Mendeley users who have this article in their library.
  • 7

    Citations

    Citations of this article.

Abstract

Background Focal spasticity is a significant motor disorder following stroke, and Botulinum Toxin Type-A (BoNT-A) is a useful treatment for this. The authors evaluated kinematic modifications induced by spasticity, and whether or not there is any improvement following injection of BoNT-A. Methods Eight patients with stroke with upper-limb spasticity, showing a flexor pattern, were evaluated using kinematics before and after focal treatment with BoNT-A. A group of sex- and age-matched normal volunteers acted as a control group. Results Repeated-measures ANOVA showed that patients with stroke performed more slowly than the control group. Following treatment with BoNT-A, there was a significant improvement in kinematics in patients with stroke, while in the control group, performance remained unchanged. Conclusions Focal treatment of spasticity with BoNT-A leads to an adaptive change in the upper limb of patients with spastic stroke.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text

Authors

  • Esteban FridmanJoan and Sanford I Weill Medical College of Cornell University

    Follow
  • Marcos CrespoFundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia

    Follow
  • Santiago Gomez Argüello

  • Lorena Degue

  • Mirta Villarreal

  • Stephan Bohlhalter

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free