The Lighter Side of a Sweet Reaction

  • Bennett B
  • Yeager M
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Abstract

The unique advantage of neutrons as biological probes is the ability to visualize hydrogen atoms in macromolecules. In this issue, Kovalevsky et al. (2010) solved an ensemble of xylose isomerase structures by neutron crystallography, and the determination of hydrogen atom rearrangements during the catalytic cycle provides insight into the enzyme's mechanism. © 2010 Elsevier Ltd.

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