A ligustilide dimer from angelica sinensis

  • Hon P
  • Lee C
  • Choang T
 et al. 
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Abstract

A novel ligustilide dimer, E-232, was isolated from the roots of Angelica sinensis. Its structure was determined by spectroscopic methods. It inhibited3H-nitrendipine binding to the dihydropyridine-sensitive calcium channel with an ic50of 4 × 10-7M. © 1990.

Author-supplied keywords

  • Angelica sinensis
  • Umbelliferae
  • calcium channel
  • ligustilide.
  • n-butylidene phthalide
  • nitrendipine
  • phthalide

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Authors

  • Po Ming Hon

  • Chi Ming Lee

  • Tai Francis Choang

  • Kuk Ying Chui

  • Henry N.C. Wong

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