Lipid Profiles of Pediatric Hematopoietic Stem Cell Transplant Survivors

  • Rodgers C
  • Gregurich M
  • Hockenberry M
  • 1


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


Cardiovascular disease (CVD) is the leading cause of death among adults in the United States. CVD pathology, including abnormal lipid levels, may begin in childhood. Hematopoietic stem cell transplant (HSCT) survivors have increased risk of abnormal lipid levels, but there is limited information in children post-HSCT. The study aimed to describe lipid levels and identify the factors associated with dyslipidemia in pediatric HSCT survivors during the first 3 years post-HSCT. This descriptive research study used a retrospective chart review to assess lipid profiles among 31 pediatric HSCT patients. Mean lipid levels were within normal limits but contained large ranges in values. There was no statistically significant change over time; however, there was an increased trend of total cholesterol and low-density lipoprotein levels and a decreased trend of high-density lipoprotein levels. The majority of patients had one abnormal lipid level at 1 and 2 years post-HSCT. Body mass index was the only factor significantly associated with dyslipidemia. An awareness of dyslipidemia among HSCT survivors may allow for early identification and treatment of abnormal lipid levels. (copyright) 2012 by Association of Pediatric Hematology/Oncology Nurses.

Author-supplied keywords

  • United States
  • adolescent
  • age
  • article
  • blood
  • body mass
  • child
  • dyslipidemia
  • female
  • hematopoietic stem cell transplantation
  • human
  • iatrogenic disease
  • lipid
  • lipid metabolism
  • male
  • pediatrics
  • preschool child
  • retrospective study
  • risk factor
  • statistical model
  • statistics
  • survivor
  • time

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • C Rodgers

  • M A Gregurich

  • M Hockenberry

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free