Antimicrobial peptide IG-25 (a truncated version of LL-37 of the cathelicidin family) tethering an azido-capped poly(ethylene glycol) chain at the N-terminus was site-specifically attached to alkynyl-terminated polymerized liposomes using copper catalyzed "click" reaction, leading to an 18 fold enhancement in efficacy against Pseudomonas aeruginosa when compared to LL-37 without any increase in cytotoxicity to human corneal epithelial cells. © The Royal Society of Chemistry 2011.
CITATION STYLE
Kumar, A., Kolar, S. S., Zao, M., McDermott, A. M., & Cai, C. (2011). Localization of antimicrobial peptides on polymerized liposomes leading to their enhanced efficacy against Pseudomonas aeruginosa. Molecular BioSystems, 7(3), 711–713. https://doi.org/10.1039/c0mb00207k
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