Long term high dose morphine, ketamine and midazolam infusion in a child with burns.

  • Cederholm I
  • Bengtsson M
  • Bjorkman S
 et al. 
  • 15


    Mendeley users who have this article in their library.
  • 25


    Citations of this article.


The metabolism of morphine and ketamine was studied in a 14 month old child with extensive burns, who received infusions of both drugs for more than 30 days. The mean plasma clearance of morphine was 29 ml min-1 kg-1 and the plasma ratios of morphine-6-glucuronide to morphine were similar to those previously reported in children. The mean plasma clearance of ketamine was 32 ml min-1 kg-1 which is greater than that previously reported in older children and adults. There were no complications despite high dose long term therapy with morphine, ketamine and midazolam.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text


  • I. Cederholm

  • M. Bengtsson

  • S. Bjorkman

  • I. Choonara

  • A. Rane

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free