Manipulation of micron-size magnetic particles of the superparamagnetic type contributes significantly in many applications like controlling the antibody/antigen binding process in immunoassays. Specifically, more target biomolecules can be attached/tagged and analyzed since the three dimensional structure of the magnetic particles increases the surface to volume ratio. Additionally, such biomolecular-tagged magnetic particles can be easily manipulated by an external magnetic field due to their superparamagnetic behavior. Therefore, magnetic particle-based immunoassays are extensively applied in micro-flow cytometry. The design of a square-loop micro-trap as a magnetic particle manipulator as well as numerical and experimental analysis is presented. Experimental results showed that the micro-trap could successfully trap and concentrate magnetic particles from a large to a small area with a high spatial range. © 2011 Published by Elsevier Ltd.
CITATION STYLE
Gooneratne, C. P., Liang, C., Giouroudi, I., & Kosel, J. (2011). A magnetic particle micro-trap for large trapping surfaces. In Procedia Engineering (Vol. 25, pp. 1201–1204). https://doi.org/10.1016/j.proeng.2011.12.296
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