Radiation therapy to the prostate involves increasingly sophisticated delivery techniques and changing fractionation schedules. With a low estimated α/β ratio, a larger dose per fraction would be beneficial, with moderate fractionation schedules rapidly becoming a standard of care. The integration of a magnetic resonance imaging (MRI) scanner and linear accelerator allows for accurate soft tissue tracking with the capacity to replan for the anatomy of the day. Extreme hypofractionation schedules become a possibility using the potentially automated steps of autosegmentation, MRI-only workflow, and real-time adaptive planning. The present report reviews the steps involved in hypofractionated adaptive MRI-guided prostate radiation therapy and addresses the challenges for implementation.
CITATION STYLE
Pathmanathan, A. U., van As, N. J., Kerkmeijer, L. G. W., Christodouleas, J., Lawton, C. A. F., Vesprini, D., … Tree, A. C. (2018, February 1). Magnetic Resonance Imaging-Guided Adaptive Radiation Therapy: A “Game Changer” for Prostate Treatment? International Journal of Radiation Oncology Biology Physics. Elsevier Inc. https://doi.org/10.1016/j.ijrobp.2017.10.020
Mendeley helps you to discover research relevant for your work.