Magnitude of underascertainment of impaired kidney function in older adults with normal serum creatinine

  • Giannelli S
  • Patel K
  • Windham B
 et al. 
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Abstract

OBJECTIVES: To estimate in a community-dwelling elderly population the magnitude of renal function misclassification, occurring when persons with normal serum creatinine have reduced glomerular filtration rate (GFR), and to describe the participant characteristics related to misclassification. DESIGN: Cross-sectional. SETTING: Population-based study of older Italian people. PARTICIPANTS: Six hundred sixty participants aged 65 to 92 with normal serum creatinine. MEASUREMENTS: GFR was estimated using the Cockcroft-Gault equation and creatinine clearance (CrCl) calculated from 24-hour urine collection. RESULTS: In participants with normal serum creatinine, 39% and 25% had moderate renal function impairment (GFR

Author-supplied keywords

  • Adult
  • Age Factors
  • Aged
  • Aged,80 and over
  • Aging
  • Algorithms
  • Biometry
  • Body Mass Index
  • Comorbidity
  • Creatinine
  • Cross-Sectional Studies
  • Demography
  • Disease
  • Female
  • Filtration
  • Glomerular Filtration Rate
  • Health
  • Humans
  • Kidney
  • Laboratories
  • Male
  • Population
  • Prevalence
  • Renal Insufficiency
  • Reproducibility of Results
  • Research
  • Risk
  • Serum
  • Severity of Illness Index
  • Sex
  • Sex Factors
  • blood
  • classification
  • complications
  • epidemiology
  • methods
  • physiopathology
  • urine

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Authors

  • S V Giannelli

  • K V Patel

  • B G Windham

  • F Pizzarelli

  • L Ferrucci

  • J M Guralnik

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