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Journal article

Management and outcome of mechanically ventilated neurological patients

Pelosi P, Ferguson N, Frutos-vivar F, Anzueto A, Putensen C, Raymondos K, Apezteguia C, Desmery P, Hurtado J, Abroug F ...see all

Critical care medicine, vol. 39, issue 6 (2011) pp. 1-11

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Objective: To describe and compare characteristics, ventilatory practices, and associated outcomes among mechanically ventilated patients with different types of brain injury and between neurologic and nonneurologic patients. Design: Secondary analysis of a prospective, observational, and multicenter study on mechanical ventilation. Setting: Three hundred forty-nine intensive care units from 23 countries. Patients: We included 552 mechanically ventilated neurologic patients (362 patients with stroke and 190 patients with brain trauma). For comparison we used a control group of 4030 mixed patients who were ventilated for nonneurologic reasons. Interventions: None. Measurements and Main Results: We collected demographics, ventilatory settings, organ failures, and complications arising during ventilation and outcomes. Multivariate logistic regression analysis was performed with intensive care unit mortality as the dependent variable. At admission, a Glasgow Coma Scale score

Author-supplied keywords

  • brain trauma
  • epidemiology
  • mechanical ventilation
  • mortality
  • outcome
  • stroke

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  • Paolo Pelosi

  • Niall D Ferguson

  • Fernando Frutos-vivar

  • Antonio Anzueto

  • Christian Putensen

  • Konstantinos Raymondos

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