Maternal vitamin D status during pregnancy and body composition and cardiovascular risk markers in Indian children: The Mysore Parthenon Study

  • G.V. K
  • S.R. V
  • N.R. W
 et al. 
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Background: Metabolic consequences of vitamin D deficiency have become a recent research focus. Maternal vitamin D status is thought to influence musculoskeletal health in children, but its relation with offspring metabolic risk is not known. Objective: We aimed to examine the association between maternal vitamin D status and anthropometric variables, body composition, and cardiovascular risk markers in Indian children. Design: Serum 25-hydroxyvitamin D [25(OH)D] concentrations were measured at 28-32 wk gestation in 568 women who delivered at Holdsworth Memorial Hospital, Mysore, India. Anthropometric variables, glucose and insulin concentrations, blood pressure, and fasting lipid concentrations were measured in the offspring at 5 and 9.5 y of age. Muscle-grip strength was measured by using a handheld dynamometer at age 9.5 y. Arm-muscle area was calculated as a measure of muscle mass. Fasting insulin resistance was calculated by using the homeostasis model assessment equation. Results: Sixty-seven percent of women had vitamin D deficiency [serum 25(OH)D concentration

Author-supplied keywords

  • 25 hydroxyvitamin D
  • Indian
  • article
  • body composition
  • cardiovascular risk
  • child
  • disease marker
  • female
  • glucose
  • glucose blood level
  • grip strength
  • human
  • human tissue
  • insulin
  • insulin blood level
  • insulin resistance
  • lipid
  • lipid blood level
  • male
  • muscle mass
  • pregnancy
  • risk assessment
  • vitamin D deficiency

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  • Krishnaveni G.V.

  • Veena S.R.

  • Winder N.R.

  • Hill J.C.

  • Noonan K.

  • Boucher B.J.

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