Measurement of central corneal thickness and pre-corneal tear film thickness of rabbits using the Scheimpflug system.

  • Dong J
  • Wu Q
  • Wang X
  • 14

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Abstract

AIM: To measure central corneal thickness (CCT) and pre-corneal tear film thickness using the Galilei dual-Scheimpflug analyzer (GSA) in New Zealand white rabbits.

METHODS: Ten normal New Zealand white rabbits (20 eyes) were included in this study. With the assistance of 0.1% fluorescein, the pre-corneal tear film can be well visualized. Both eyes of each rabbit were scanned once with the GSA pre- and post-instillation of 1µL 0.1% fluorescein. The difference between the two measurements of CCT (4-mm diameter) was recorded as the pachymetric values of the central tear film.

RESULTS: The CCT of pre- and post-instillation was 388.8±9.5µm and 407.0±10.5µm, respectively. After a paired t-test analysis, the central pre-corneal tear film thickness of 4mm diameter was 18.2±5.31µm with a 95% confidence interval of (15.7, 20.6)µm (P
CONCLUSION: GSA can be used to measure CCT and analyze central tear film thickness of rabbits with the help of fluorescein.

Author-supplied keywords

  • 05
  • 10
  • 2013
  • 2222-3959
  • 3980
  • central
  • corneal thickness
  • doi
  • fluorescein
  • issn
  • j
  • rabbits
  • scheimpflug
  • tear film

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Authors

  • Jing Dong

  • Qiang Wu

  • Xiao-Gang Wang

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