Measurement of leukotrienes in humans

  • Kumlin M
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This article focuses on strategies to appreciate in vivo release of the cysteinyl-leukotrienes (LTs; LTC4, LTD4, and LTE4) and presents some results obtained by such measurements. Whereas analyses of leukotriene formation in isolated tissues and cells primarily reflect ex vivo biosynthesis, measurement of intact leukotrienes or metabolites thereof in different biological fluids may be used as an index of in vivo production of the primary leukotrienes.

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  • Maria Kumlin

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