Mechanical properties of elastin along the thoracic aorta in the pig

  • Lillie M
  • Gosline J
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Abstract

Understanding the mechanical environment of each component within the arterial wall is fundamental for understanding vascular growth and remodelling and for engineering artificial vascular conduits. We have investigated the mechanical status of arterial elastin by measuring the circumferential mechanical properties of purified elastin as function of position along the descending thoracic aorta of the pig. The tensile circumferential secant modulus, Esec, measured in uniaxial mechanical tests, increased 30% (P

Author-supplied keywords

  • Aorta
  • Elastin
  • Mechanical properties
  • Tissue engineering

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Authors

  • M. A. Lillie

  • J. M. Gosline

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