Metagenomic screening for bleomycin resistance genes

  • Mori T
  • Mizuta S
  • Suenaga H
 et al. 
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Abstract

A metagenomic library of activated sludge was screened for bleomycin resistance genes. Two genes were identified that differed greatly from each other, from the genes of bleomycin-producing actinomycetes, and from those of clinical isolates. Therefore, the nonclinical environment is a rich reservoir of new resistance elements, and metagenomics can be used to sample the resistome rapidly.

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Authors

  • Toshio Mori

  • Shiori Mizuta

  • Hikaru Suenaga

  • Kentaro Miyazaki

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