Microfabricated nerve-electrode interfaces in neural prosthetics and neural engineering

  • Song Y
  • Ibrahim A
  • Rabie A
 et al. 
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Neural interfaces and implants are finding more clinical applications and there are rapid technological advances for more efficient and safe design, fabrication and materials to establish high-fidelity neural interfaces. In this review paper, we highlight new developments of the microfabricated electrodes and substrates with regard to the design, materials, fabrication and their clinical applications. There is a noticeable trend towards integration of microfluidic modules on a single neural platform. In addition to the microelectrodes for neural recording and stimulation, microfluidic channels are integrated into a nerve-electrode interface to explore the rich neurochemistry present at the neural interface and exploit it for enhanced electrochemical stimulation and recording of the central and peripheral nervous system.

Author-supplied keywords

  • MEMS
  • Microelectrode array
  • Microfabrication
  • Neural engineering
  • Neural implant
  • Neural prosthetics

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  • Jongyoon HanMassachusetts Institute of Technology

  • Yong Ak Song

  • Ahmed M.S. Ibrahim

  • Amr N. Rabie

  • Samuel J. Lin

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