Microfluidic blood plasma separation via bulk electrohydrodynamic flows

  • Arifin D
  • Yeo L
  • Friend J
  • 58


    Mendeley users who have this article in their library.
  • 31


    Citations of this article.


An effective mechanism for rapid and efficient microfluidic particle trapping and concentration is proposed without requiring any mechanically moving parts. When a voltage beyond the threshold atmospheric ionization value is applied on a sharp electrode tip mounted at an angle above a microfluidic liquid chamber, the bulk electrohydrodynamic air thrust that is generated results in interfacial shear and, hence, primary azimuthal liquid surface recirculation. This discharge driven vortex mechanism, in turn, causes a secondary bulk meridional liquid recirculation, which produces an inward radial force near the bottom of the chamber. Particles suspended in the liquid are then rapidly convected by the bulk recirculation toward the bottom, where the inward radial force causes them to spiral in a helical swirl-like fashion toward a stagnation point. In particular, we show that these flows, similar to Batchelor flows occurring in a cylindrical liquid column between a stationary and rotating disk, can be used for the separation of red blood cells from blood plasma in a miniaturized device.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Dian R. Arifin

  • Leslie Y. Yeo

  • James R. Friend

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free