A mild chemically cleavable linker system for functional proteomic applications

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Abstract

(Chemical Equation Presented) An amicable split: Small-molecule probes can be applied for the enrichment of specific protein targets from a complex proteome. A cleavable linker system, which prevents the release of unwanted, nonspecifically bound proteins, can be used for a very mild and highly selective cleavage of probe-labeled proteins. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

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Verhelst, S. H. L., Fonović, M., & Bogyo, M. (2007). A mild chemically cleavable linker system for functional proteomic applications. Angewandte Chemie - International Edition, 46(8), 1284–1286. https://doi.org/10.1002/anie.200603811

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