Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration © 2012 Landes Bioscience . Do not distribute . © 2012 Landes Bioscience . Do not distribute .

  • Zheng Y
  • Tesar D
  • Benincosa L
 et al. 
  • 4

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Author-supplied keywords

  • a abs
  • abbreviations
  • amount of the drug
  • animal model
  • anti-therapeutic antibodies
  • ata
  • bioavailability
  • c c
  • c p
  • central compartment
  • cl
  • cl humans
  • cl minipigs
  • clearance
  • clearance in humans
  • clearance in minipig
  • contract research
  • cro
  • depot
  • drug concentration in the
  • drug concentrations in the
  • f
  • fcrn
  • fraction absorbed
  • in the absorption site
  • mab igg
  • minipig
  • neonatal fc receptor
  • peripheral compartment
  • pharmacokinetics
  • subcutaneous bioavailability
  • β 2 -microglobulin
  • β 2 m

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Authors

  • Yanan Zheng

  • Devin B Tesar

  • Lisa Benincosa

  • Herbert Birnböck

  • C Andrew Boswell

  • Daniela Bumbaca

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