Model-based Iterative Reconstruction and Adaptive Statistical Iterative Reconstruction Techniques in Abdominal CT: Comparison of Image Quality in the Detection of Colorectal Liver Metastases

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  • A. B
  • M. H
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Purpose: To prospectively evaluate dose reduction and image quality characteristics of abdominal computed tomographic (CT) scans reconstructed with model-based iterative reconstruction (MBIR) compared with adaptive statistical iterative reconstruction (ASIR) in oncology patients with colorectal liver metastases. Materials and Methods: The study complied with HIPAA guidelines and was approved by the ethics committee of the institutional review board. All patients gave written informed consent. Fiftyone patients with colorectal liver metastases underwent body CT (thorax and abdomen) with a 64-section multidetector unit. With a radiation dose reduction by 2.36 mGy compared to standard of care CT with ASIR 50% (radiation dose, 7.54 mGy), MBIR can provide diagnostically acceptable CT scans without compromising image quality. Two radiologists independently assessed randomized images in a blinded manner. Imaging sets were compared for lesion detection, lesion conspicuity, overall image quality, and signal-to-noise ratio with a paired sample t test. Inter- and intraobserver agreement was assessed with the Cohen k. Results: The mean volume CT dose index was 5.18 mGy +/- 0.76, mean dose-length product 374 mGy +/- cm 6 63.47, mean effective diameter 29.38 cm +/- 3.46, and mean size-specific dose estimate 6.52 mGy 6 0.73. In small liver lesions (

Author-supplied keywords

  • *adaptive statistical iterative reconstruction
  • *colorectal liver metastasis
  • *colorectal liver metastasis/di [Diagnosis]
  • *image quality
  • *image reconstruction
  • *model based iterative reconstruction
  • *multidetector computed tomography
  • Student t test
  • abdomen
  • adult
  • aged
  • article
  • artifact
  • cancer diagnosis
  • comparative study
  • computer assisted tomography
  • cone beam computed tomography
  • controlled study
  • diagnosis
  • dosimetry
  • double blind procedure
  • drug dose reduction
  • female
  • health care quality
  • human
  • image analysis
  • image quality
  • imaging
  • informed consent
  • institutional review
  • liver
  • liver injury
  • major clinical study
  • male
  • model
  • noise
  • oncology
  • patient
  • priority journal
  • professional standard
  • prospective study
  • qualitative analysis
  • quantitative analysis
  • radiation dose
  • radiation dose reduction
  • radiologist
  • randomized controlled trial
  • signal noise ratio
  • thorax
  • tumor volume

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  • Volders D.

  • Bols A.

  • Haspeslagh M.

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