Modulation of epithelial cell growth by intraepithelial gamma delta T cells.

  • Boismenu R
  • Havran W
  • 19


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


The role played in immune surveillance by gamma delta T cells residing in various epithelia has not been clear. It is shown here that activated gamma delta T cells obtained from skin and intestine express the epithelial cell mitogen keratinocyte growth factor (KGF). In contrast, intraepithelial alpha beta T cells, as well as all lymphoid alpha beta and gamma delta T cell populations tested, did not produce KGF or promote the growth of cultured epithelial cells. These results suggest that intraepithelial gamma delta T cells function in surveillance and in repair of damaged epithelial tissues.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • R Boismenu

  • W L Havran

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free