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Modulation of humoral immune responses by Tinospora malabarica in experimental animals

Bhattacharya S, Maity P, Mediratta P, Sen P ...see all

Indian Journal of Experimental Biology, vol. 29, issue 10 (1991) pp. 971-972

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Effect of alkaloidal fraction of aqueous extract of T. malabarica (Tm) was studied on humoral antibody responses in rats and guineapigs. The anti-SRBC haemagglutination titre was found to be enhanced in rats pretreated with Tm (2.5 mg/kg). Passive cutaneous anaphylaxis (PCA) in rats was also increased in Tm treated group. In vitro experiments with sensitized rat peritoneal mast cells showed a significant decrease in antigen-induced various spasmogens on isolated guineapig ileum.

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  • PUI: 21290610
  • PMID: 1726092
  • SCOPUS: 2-s2.0-0025886661
  • ISSN: 00195189
  • SGR: 0025886661


  • S. K. Bhattacharya

  • P. C. Maity

  • P. Mediratta

  • P. Sen

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