Mortality trends associated with acute renal failure requiring dialysis after CABG surgery in the United States

  • A. N
  • U.D. P
  • B.G. P
 et al. 
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Abstract

Background/Aims: Acute renal failure is associated with a high risk of mortality when it complicates coronary artery bypass graft (CABG) surgery. We examined a large nationwide database from 1988 to 2003 and hypothesized that mortality in CABG-associated acute renal failure needing dialysis (ARF-D) had declined during this period. Methods: The Nationwide Inpatient Sample containing data on inpatient stays across 20% of US hospitals was used for our study. Multivariate logistic regression was used to determine an association between year and ARF-D mortality with standardized risk adjustment. Results: Incidence of ARF-D increased from 0.2 to 0.6% while mortality simultaneously decreased from 47.4% in 1988 to 29.7% in 2003. In the multivariable model, year was significantly associated with declining ARF-D mortality. Conclusions: The incidence of post-CABG ARF-D more than doubled from 1988 to 2003, while mortality simultaneously decreased by over one-third. Improved survival after ARF-D following CABG may be counterbalanced by increased morbidity and resource utilization. Copyright 2009 S. Karger AG, Basel.

Author-supplied keywords

  • *acute kidney failure/ep [Epidemiology]
  • *coronary artery bypass surgery
  • United States
  • article
  • dialysis
  • female
  • human
  • major clinical study
  • male
  • morbidity
  • mortality
  • priority journal

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Authors

  • Nicoara A.

  • Patel U.D.

  • Phillips-Bute B.G.

  • Shaw A.D.

  • Stafford-Smith M.

  • Milano C.A.

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