Natural Killer Cell Memory

  • O'Sullivan T
  • Sun J
  • Lanier L
 et al. 
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Abstract

Natural killer (NK) cells have historically been considered short-lived cytolytic cells that can rapidly respond against pathogens and tumors in an antigen-independent manner and then undergo cell death. Recently, however, NK cells have been shown to possess traits of adaptive immunity and can acquire immunological memory in a manner similar to that of T and B cells. In this review, we discuss evidence of NK cell memory and the mechanisms involved in the generation and survival of these innate lymphocytes.

Author-supplied keywords

  • Cytomegalovirus
  • Immunological memory
  • Natural killer cells

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Authors

  • Timothy E. O'Sullivan

  • Joseph C. Sun

  • Lewis L. Lanier

  • Timothy E O Sullivan

  • Joseph C. Sun

  • Lewis L. Lanier

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