Journal article

Neurobiology of impulsivity and the impulse control disorders.

Stein D, Hollander E, Liebowitz M ...see all

The Journal of neuropsychiatry and clinical neurosciences, vol. 5, issue 1 (1993) pp. 9-17

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Clinical impulsivity has been characterized in both dimensional and categorical terms. Whereas DSM-III-R classifies personality disorders characterized by impulsivity and impulse control disorders as discrete entities, impulsive symptoms and traits can also be conceived in terms of an underlying behavioral dimension. The authors review research on impulsivity and the impulse control disorders from a biological perspective. In particular, they critically review evidence that the serotonin neurotransmitter system mediates symptoms and traits of impulsive personality disorders and the impulse control disorders.

Author-supplied keywords

  • Adult
  • Brain Chemistry
  • Drug Therapy
  • Female
  • Humans
  • Hydroxyindoleacetic Acid
  • Hydroxyindoleacetic Acid: analysis
  • Hydroxyindoleacetic Acid: cerebrospinal fluid
  • Impulsive Behavior
  • Impulsive Behavior: blood
  • Impulsive Behavior: cerebrospinal fluid
  • Impulsive Behavior: drug therapy
  • Male
  • Middle Aged
  • Personality Disorders
  • Personality Disorders: cerebrospinal fluid
  • Personality Disorders: diagnosis
  • Personality Disorders: drug therapy
  • Psychiatric Status Rating Scales
  • Serotonin
  • Serotonin: analysis
  • Serotonin: cerebrospinal fluid
  • Serotonin: deficiency
  • Suicide

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  • D J Stein

  • E Hollander

  • M R Liebowitz

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