Neuromimetic ICs and system for parameters extraction in biological neuron models

Abstract

This paper presents an analog neuromimetic integrated circuit and an associated system dedicated for experiments of parameters extraction in biological neuron models. The IC based on Hodgkin-Huxley (HH) formalism computes in real-time and continuous mode. The dedicated system is a PCI board that is able to program dynamically the neuron model parameters in the IC. The full system, which includes the IC and the PCI board, is used to build a new hardware/software technique to extract biophysics parameters from biological neuron. This technique could be helpful for the neuroscientists proposing an alternative to voltage-clamp technique. For that, the new technique will use optimization algorithms to be efficient. © 2006 IEEE.