How do neutrophils and pathogens interact?

  • Mayer-Scholl A
  • Averhoff P
  • Zychlinsky A
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Abstract

Many pathogens can manipulate macrophages after phagocytosis yet are efficiently killed by neutrophils. This poses the question of whether neutrophils have mechanisms that enable them to specifically recognise pathogens and have pathogens evolved mechanisms to modulate neutrophil function? Here, we review recent work on neutrophils and their interaction with four different bacteria: Staphylococcus aureus, Helicobacter pylori, Anaplasma phagocytophilum and members of the Enterobacteriae family.

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Authors

  • Anne Mayer-Scholl

  • Petra Averhoff

  • Arturo Zychlinsky

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