A new recursive approach for reconstructing metabolic networks from KEGG

  • Zhou T
  • Wang Z
  • Yung S
 et al. 
  • 9


    Mendeley users who have this article in their library.
  • 0


    Citations of this article.


The high-quality network reconstruction from metabolites, enzymes and reactions is the first essential step for the studies on the metabolic networks. Previously the approach based on the KEGG/LIGAND database can only reconstruct the organism-level metabolic networks and the network quality is quite doubtful. In this paper we propose a new recursive approach to reconstruct metabolic networks. The data selection mechanism of KEGG/PATHWAY ensures that metabolic networks are parsimonious but reliable. The KO system makes it possible to generate networks hierarchically. The KEGG web service manages to keep the data up-to-date. Results of comparison with the previous approach show our new approach is practical and reliable.

Author-supplied keywords

  • KEGG
  • Metabolic network
  • Network reconstruction
  • Web service

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text


  • Tingting Zhou

  • Zhenghua Wang

  • Samuel K F Yung

  • Yunping Zhu

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free