Nickel-Catalyzed C-O/C-H Cross-Coupling Reactions for C-C Bond Formation

  • Chen T
  • Han L
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Halides not required: Nickel-catalyzed C[BOND]O/C[BOND]H cross-couplings for the construction of C[BOND]C bonds have recently been disclosed. By carefully optimizing the nickel catalyst, new C[BOND]C bond-forming reactions were developed, and even quaternary stereogenic centers are now accessible in high yields from readily available phenoxide derivatives and hydrocarbons.

Author-supplied keywords

  • C-H activation
  • C-O activation
  • asymmetric catalysis
  • cross-coupling
  • nickel catalysis

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  • Tieqiao Chen

  • Li Biao Han

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