NMR studies of structure and function of biological macromolecules (Nobel Lecture)

Abstract

The structure of proteins (such as that of bovine prion protein, see picture) and further information on the dynamics and structural, thermodynamic, and kinetic aspects of their interactions with other components in solution can be obtained by NMR methods developed by K. Wüthrich and his group. In his Nobel Lecture, Wüthrich delves into the past, present, and future of these techniques, and offers us a glimpse into his life.