A Novel Pathogenic Taxon of the Mycobacterium tuberculosis Complex, Canetti: Characterization of an Exceptional Isolate from Africa

  • Van Soolingen D
  • Hoogenboezem T
  • De Haas P
 et al. 
  • 135


    Mendeley users who have this article in their library.
  • 212


    Citations of this article.


In an attempt to characterize an unusual mycobacterial strain isolated from a 2-year-old Somali patient with lymphadenitis, we applied various molecular methods not previously used for the taxonomic classification of mycobacteria. This isolate, designated So93, did not differ from Mycobacteriurn tuberculosis in the biochemical tests and in its 16s rRNA sequence, but produced smooth and glossy colonies, which is highly exceptional for this species. This smooth phenotype was unstable and switched nonreversibly to a rough colony morphology with a low frequency. The two colony types were equally virulent for the guinea pig, exhibiting characteristic

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • D. Van Soolingen

  • T. Hoogenboezem

  • P. E. W. De Haas

  • P. W. M. Hermans

  • M. A. Koedam

  • K. S. Teppema

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free