Novel polymorphisms in the upstream region of the human dopamine D4 receptor (DRD4) gene.

  • Mitsuyasu H
  • Ozawa H
  • Takeda Y
 et al. 
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Abstract

We found nine novel polymorphisms in the upstream region of the human dopamine D4 receptor (DRD4) gene of Japanese by direct sequencing. These polymorphisms are -809G > A, -768G > A, -616C > G, -603T > del, -602G > del, -600G > C, -376C > T, -291C > T, and -128G > T. One known polymorphism, -521C > T, was also recognized. Six of these sites were identified as restriction fragment length polymorphisms (RFLPs).

Author-supplied keywords

  • Dopamine D2
  • Dopamine D2: genetics
  • Dopamine D4
  • Genetic
  • Genetic: genetics
  • Humans
  • Polymorphism
  • Promoter Regions
  • Receptors

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Authors

  • H Mitsuyasu

  • H Ozawa

  • Y Takeda

  • Y Fukumaki

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