Natural resistance-associated macrophage proteins (Nramp) are multispecific symporters facilitating proton-dependent import of divalent metals. Nramp1 restricts microbial access to essential micro-nutrients such as iron and manganese within professional phagosomes. Increased understanding of Nramp1 roles in human phagocytes will be useful for future therapeutic approaches against selected infectious and immune diseases. © 2007 Elsevier Masson SAS. All rights reserved.
CITATION STYLE
Cellier, M. F., Courville, P., & Campion, C. (2007). Nramp1 phagocyte intracellular metal withdrawal defense. Microbes and Infection, 9(14–15), 1662–1670. https://doi.org/10.1016/j.micinf.2007.09.006
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