Ochratoxin A, a known mycotoxin with demonstrated toxicity to insects, has been isolated from the sclerotia of the fungus Aspergillus carbonarius NRRL 369. The sclerotia, harvested from a solid substrate fermentation of corn kernels at 28°C, produced quantities of ochratoxin A exceeding 50 ppm/g dry weight of sclerotia. Evidence is presented that ochratoxin A accounts for the activity of the methanol extract against larvae of the detritivorous beetle Carpophilus hemipterus (Nitidulidae) (75% reduction in feeding rate) and corn ear worm Helicoverpa zea (50% mortality with 99% reduction in weight gain among surviving larvae) when incorporated into a pinto bean diet at levels less than those occurring naturally in the sclerotia.
CITATION STYLE
Wicklow, D. T., Dowd, P. F., Alfatafta, A. A., & Gloer, J. B. (1996). Ochratoxin A: An antiinsectan metabolite from the sclerotia of Aspergillus carbonarius NRRL 369. Canadian Journal of Microbiology, 42(11), 1100–1103. https://doi.org/10.1139/m96-141
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