Ocular biometry and open-angle glaucoma: The los angeles latino eye study

  • Kuzin A
  • Varma R
  • Reddy H
 et al. 
  • 35

    Readers

    Mendeley users who have this article in their library.
  • 43

    Citations

    Citations of this article.

Abstract

Purpose: To examine the associations among myopic refractive error (MRE), corneal power (CP), axial length (AL), and the prevalence of open-angle glaucoma (OAG) in an adult Latino population. Design: Population-based, cross-sectional epidemiologic study. Participants: A total of 5927 Latinos aged 40 years and older in the Los Angeles Latino Eye Study (LALES). Methods: Myopic refractive error was defined as a non-cycloplegic sphero-cylindrical refractive error of ≤-1 diopter (D). Axial length was measured by A-scan ultrasound. Corneal power was measured using a Humphrey auto-refractor. Open-angle glaucoma was diagnosed by a combination of optic nerve and visual field changes. Pseudophakic and aphakic eyes were excluded from the analysis. The associations among MRE, AL, CP, and the prevalence of OAG were calculated using a logistic regression model, adjusting for age, gender, intraocular pressure, central corneal thickness, diabetes mellitus, family history of glaucoma, and lens nuclear opacification (NO). Main Outcome Measures: Odds ratios (OR) for the prevalence of OAG. Results: After adjusting for covariates, persons with greater MRE (OR 1.82; confidence interval [CI], 1.20-2.77; P = 0.005), longer AL (OR 1.25; CI, 1.03-1.50; P = 0.02), and flatter corneas (OR 1.21; CI, 1.08-1.35; P = 0.0007) were associated with a higher prevalence of OAG when compared with those with emmetropic refractive error, shorter AL, and steeper corneas. Conclusions: Persons with an MRE, flatter corneas, and longer ALs should be considered to be at higher risk of having OAG. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. © 2010 American Academy of Ophthalmology.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Aaron A. Kuzin

  • Rohit Varma

  • Harsha S. Reddy

  • Mina Torres

  • Stanley P. Azen

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free