Optimal control for combination therapy in cancer

  • Ledzewicz U
  • Schattler H
  • D'Onofrio A
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Abstract

A mathematical model for the scheduling of angiogenic inhibitors in combination with a killing agent is considered as an optimal control problem. Initial results on the structure of optimal controls are derived.

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Authors

  • Urszula Ledzewicz

  • Heinz Schattler

  • Alberto D'Onofrio

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