Oral medication adherence and disease severity in pediatric inflammatory bowel disease.

  • Hommel A. K
  • Denson A. L
  • Baldassano N. R
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OBJECTIVE: The purpose of this study was to examine the relationship of oral medication adherence and perceived adherence barriers with disease severity in a sample of adolescents with inflammatory bowel disease (IBD). METHODS: Participants included 62 adolescents, aged 13-17 years, diagnosed with IBD, and their parents. Data on the measures of parent-rated and patient-rated oral medication adherence and related barriers, behavioral and emotional functioning per parent report and self-report, and disease severity per medical chart reported by a physician were obtained. RESULTS: Fifteen percent of the sample reported clinically elevated depressive symptoms and 24% reported clinically elevated internalizing behavioral problems. Number of reported adherence barriers was 2.6±1.5, and none of the participants reported zero barriers. Parental ratings of medication adherence (t=-2.11, P

Author-supplied keywords

  • Adolescence
  • Behavior
  • Data Analysis Software
  • Descriptive Statistics
  • Female
  • Funding Source
  • Human
  • Inflammatory Bowel Diseases -- Drug Therapy -- In
  • Linear Regression
  • Male
  • Multivariate Analysis
  • Ohio
  • Patient Compliance
  • Pearson's Correlation Coefficient
  • Pennsylvania
  • Severity of Illness
  • Summated Rating Scaling
  • T-Tests

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  • Kevin Hommel A.

  • Lee Denson A.

  • Robert Baldassano N.

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