Organizational development trajectory of a large academic radiotherapy department set up similarly to a prospective clinical trial: The MAASTRO experience

  • Jacobs M
  • Boersma L
  • Dekker A
 et al. 
  • 7


    Mendeley users who have this article in their library.
  • 0


    Citations of this article.


OBJECTIVE: To simultaneously improve patient care processes and clinical research activities by starting a hypothesis-driven reorganization trajectory mimicking the rigorous methodology of a prospective clinical trial. METHODS: The design of this reorganization trajectory was based on the model of a prospective trial. It consisted of (1) listing problems and analysing their potential causes, (2) defining interventions, (3) defining end points and (4) measuring the effect of the interventions (i.e. at baseline and after 1 and 2 years). The primary end point for patient care was the number of organizational root causes of incidents/near incidents; for clinical research, it was the number of patients in trials. There were several secondary end points. We analysed the data using two sample z-tests, chi(2) test, a Mann-Whitney U test and the one-way analysis of variance with Bonferroni correction. RESULTS: The number of organizational root causes was reduced by 27% (p < 0.001). There was no effect on the percentage of patients included in trials. CONCLUSION: The reorganizational trajectory was successful for the primary end point of patient care and had no effect on clinical research. Some confounding events hampered our ability to draw strong conclusions. Nevertheless, the transparency of this approach can give medical professionals more confidence in moving forward with other organizational changes in the same way. ADVANCES IN KNOWLEDGE: This article is novel because managerial interventions were set up similarly to a prospective clinical trial. This study is the first of its kind in radiotherapy, and this approach can contribute to discussions about the effectiveness of managerial interventions.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Andre DekkerMaastricht Universitair Medisch Centrum+

  • M. Jacobs

  • L. Boersma

  • E. Hermanns

  • R. Houben

  • M. Govers

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free