Dermatomyositis (DM) is an idiopathic inflammatory myopathy associated with characteristic skin manifestations. In 15-20% of patients present with dysphagia, it is associated with nutritional deficiency, predisposition to aspiration pneumonia, decreased quality of life and a poor prognosis. There is a well-recognized association between DM and malignancies, including ovarian, breast, lung, and colon cancer. We report a case of a male patient aged 85 with DM associated with colon adenocarcinoma; progressive dysphagia was the first manifestation, and subsequently proximal muscle weakness and typical skin lesions were present. Given the clinical suspicion of DM as a paraneoplastic syndrome, tumor markers were order and a high carcinoembryonic antigen was found. A colonoscopy study and histopathologic examination revealed the presence of adenocarcinoma of the colon.
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Espinoza-Cobos, J. C., Pérez-Figueroa, J., Zúñiga-Ahuet, G., Dorantes, M. A., Grube-Pagola, P., Ruíz-Juárez, I., & Remes-Troche, J. M. (n.d.). [Oropharyngeal dysphagia as a first manifestation of dermatomyositis associated with colon cancer]. Revista de Gastroenterologia de Mexico, 75(4), 522–7. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21169124
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