Osteoblast cell adhesion on a laser modified zirconia based bioceramic

  • Hao L
  • Lawrence J
  • Chian K
  • 43

    Readers

    Mendeley users who have this article in their library.
  • 72

    Citations

    Citations of this article.

Abstract

Due to their attractive mechanical properties, bioinert zirconia bioceramics are frequently used in the high load-bearing sites such as orthopaedic and dental implants, but they are chemically inert and do not naturally form a direct bond with bone and thus do not provide osseointegration. A CO2 laser was used to modify the surface properties with the aim to achieve osseointegration between bioinert zirconia and bone. The surface characterisation revealed that the surface roughness decreased and solidified microstructure occurred after laser treatment. Higher wettability characteristics generated by the CO2 laser treatment was primarily due to the enhancement of the surface energy, particularly the polar component, determined by microstructural changes. An in vitro test using human fetal osteoblast cells (hFOB) revealed that osteoblast cells adhere better on the laser treated sample than the untreated sample. The change in the wettability characteristics could be the main mechanism governing the osteoblast cell adhesion on the YPSZ. (C) 2005 Springer Science + Business Media, Inc.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text

Authors

  • L. Hao

  • J. Lawrence

  • K. S. Chian

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free