An overview of assessment of prognostic and predictive factors in breast cancer needle core biopsy specimens

  • Rakha E
  • Ellis I
  • 1

    Readers

    Mendeley users who have this article in their library.
  • N/A

    Citations

    Citations of this article.

Abstract

Needle core biopsy (NCB), as part of triple assessment for preoperative evaluation and diagnosis of breast cancer, is now considered as an established, highly accurate method for diagnosing breast cancer that has replaced either fine needle aspiration cytology or excisional biopsy as the initial diagnostic biopsy procedures in many institutions. In addition to its primary role in establishing an accurate histological diagnosis, NCB can potentially provide important additional pathological prognostic information which may be of direct clinical value in certain situations, such as patients being considered for preoperative (neoadjuvant) therapy. With this background in mind we briefly review the current role of NCB in breast cancer diagnosis and then concentrate this review on the usefulness and issues relating to use of this technique in providing accurate, reliable and clinically relevant preoperative prognostic and predictive information in patients with breast cancer.;Needle core biopsy (NCB), as part of triple assessment for preoperative evaluation and diagnosis of breast cancer, is now considered as an established, highly accurate method for diagnosing breast cancer that has replaced either fine needle aspiration cytology or excisional biopsy as the initial diagnostic biopsy procedures in many institutions. In addition to its primary role in establishing an accurate histological diagnosis, NCB can potentially provide important additional pathological prognostic information which may be of direct clinical value in certain situations, such as patients being considered for preoperative (neoadjuvant) therapy. With this background in mind we briefly review the current role of NCB in breast cancer diagnosis and then concentrate this review on the usefulness and issues relating to use of this technique in providing accurate, reliable and clinically relevant preoperative prognostic and predictive information in patients with breast cancer.;

Author-supplied keywords

  • Accuracy
  • Automation
  • Biomarkers
  • Biopsy
  • Biopsy, Needle
  • Biopsy, Needle - methods
  • Breast Neoplasms - diagnosis
  • Breast Neoplasms - pathology
  • Breast Neoplasms - surgery
  • Breast cancer
  • Calcification
  • Cancer patients
  • Cancer therapies
  • Deoxyribonucleic acid--DNA
  • Development and progression
  • Diagnosis
  • Evaluation
  • Gangrene
  • Gene expression
  • Pathology
  • Prognosis
  • Tumor Markers, Biological - analysis
  • Tumors
  • Ultrasonic imaging
  • Usage

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • E A Rakha

  • I O Ellis

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free