Oxidative stress tests: Overview on reliability and use. Part II

  • Palmieri B
  • Sblendorio V
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– Monitoring oxidative stress\r
in humans is achieved by assaying products of\r
oxidative damage or by investigating the potential\r
of an organism, tissue or body fluids to\r
withstand further oxidation. Unfortunately,\r
there is little consensus concerning the selection\r
of parameters of oxidative stress or antioxidant\r
state to be determined in defined patients\r
or diseases. This is not only due to the\r
uncertainty wheter or not a certain parameter\r
is playing a causative role. Moreover, the\r
methods of determination described in the literature\r
represent very different levels of analytical\r
practicability, costs, and quality. Generally\r
accepted reference ranges and interpretations\r
of pathological situations are lacking as\r
well as control materials. At present, the situation\r
is changing dramatically and sophisticated\r
methods like HPLC (High Performance Liquid\r
Chromatography) and immunochemical determinations\r
have become more and more\r
common standard.

Author-supplied keywords

  • Antioxidants
  • Free radicals
  • Oxidative stress
  • Reactive oxygen species

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  • PMID: 18306907
  • SGR: 39049134335
  • SCOPUS: 2-s2.0-39049134335
  • PUI: 351233583
  • ISBN: 1128-3602
  • ISSN: 11283602


  • B. Palmieri

  • V. Sblendorio

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