Pancreatic islets are very poor in rectifying oxidative DNA damage

  • Modak M
  • Parab P
  • Ghaskadbi S
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Free radicals that escape scavenging by antioxidant defense damage lipids, proteins, and DNA. Damage to DNA can be repaired. Therefore, both cells' antioxidant defense and their ability to repair oxidatively damaged DNA decide its fate to survive oxidative stress. Pancreatic islets cells with poor antioxidant defense were checked for their ability to remove oxidative damage form DNA.

Author-supplied keywords

  • 8-OHdG
  • DNA repair
  • Oxidative DNA damage

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  • Manisha A. Modak

  • Pradeep Bhaskar Parab

  • Saroj S. Ghaskadbi

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