Pancreatic islets are very poor in rectifying oxidative DNA damage

  • Modak M
  • Parab P
  • Ghaskadbi S
  • 12

    Readers

    Mendeley users who have this article in their library.
  • 33

    Citations

    Citations of this article.

Abstract

Free radicals that escape scavenging by antioxidant defense damage lipids, proteins, and DNA. Damage to DNA can be repaired. Therefore, both cells' antioxidant defense and their ability to repair oxidatively damaged DNA decide its fate to survive oxidative stress. Pancreatic islets cells with poor antioxidant defense were checked for their ability to remove oxidative damage form DNA.

Author-supplied keywords

  • 8-OHdG
  • DNA repair
  • Oxidative DNA damage

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Manisha A. Modak

  • Pradeep Bhaskar Parab

  • Saroj S. Ghaskadbi

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free