Abstract
Although the clinical and laboratory features of pseudotumor cerebri have been clearly delineated, the pathogenesis of idiopathic pseudotumor remains a mystery. A number of pathogenetic mechanisms have been proposed to account for some or all of the observed cases. We describe a model relating changes in CSF outflow resistance and/or dural sinus venous pressure to observed changes in (i) CSF pressure, (ii) cerebral blood volume and (iii) the volume and hydrodynamic flow resistance of the ventriculosubarachnoid space. © 1980, All rights reserved.
Author supplied keywords
- CBV
- CSF
- CSFP
- ICP
- If
- PVI
- Pd
- R1s
- Ra
- Rs
- Rt
- SVP
- arachnoid villous flow resistance
- cerebral blood volume
- cerebrospinal fluid
- cerebrospinal fluid pressure
- dural sinus venous pressure
- flow resistance of the convexity subarachnoid space
- intracranial pressure
- limiting value of Rs
- pressure-volume index
- rate of CSF formation
- subarachnoid venous pressure
- total CSF outflow resistance
Cite
CITATION STYLE
Aisenberg, R. M., & Rottenberg, D. A. (1980). The pathogenesis of pseudotumor cerebri: A mathematical analysis. Journal of the Neurological Sciences, 48(1), 51–60. https://doi.org/10.1016/0022-510X(80)90149-5
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