Pax6 regulation in retinal cells by CCCTC binding factor

  • Li T
  • Lu Z
  • Lu L
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Abstract

A previous study demonstrated that CTCF (CCCTC binding factor) regulates homeobox Pax6 gene expression in early embryonic stages and plays a dominant role in eye development. The purpose of the present study was to explore further the mechanism of CTCF controlling Pax6 gene expression in human retinoblastoma (Rb) cells and in the development of chicken and mouse retinas.

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Authors

  • Tie Li

  • Zhenyu Lu

  • Luo Lu

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