PD-1 expression on peripheral CD8+ TEM/TEMRA subsets closely correlated with HCV viral load in chronic hepatitis C patients

  • Shen T
  • Zheng J
  • Xu C
 et al. 
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Abstract

Tight correlation between host circulating CD8+ T cell-mediated immune response and control of viral replication is classical characteristic of long-term HCV infection. CD8+ T cell maturation/activation markers are expected to be associated with viral replication and disease progression in chronic HCV infection. The aim of the present study was to explore novel markers on CD8+ T cells with ability to evaluate HCV viral replication and disease progression.

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Authors

  • Tao Shen

  • Jiajia Zheng

  • Chunhui Xu

  • Jia Liu

  • Weidong Zhang

  • Fengmin Lu

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