In recent years there has been increasing interest in the relation between periodontal disease and cardiovascular disease. Several studies have supported the notion that individuals with periodontitis have a greater risk of developing coronary heart disease than those who had little or no periodontal infection. Periodontal disease may predispose affected individuals to coronary heart disease by elevating systemic C-reactive protein level and pro-inflammatory activity and accelerate development of coronary heart disease. According to Buhlin et al, individuals with periodontal disease had significantly higher level of circulating monocytes, C-reactive protein and lower levels of HDL-cholesterol, in comparison with the controls. This study suggests that periodontal disease, once considered a purely local disease, may cause systemic inflammation and lipid changes known to increase the risk of coronary heart disease. However, other investigators disagreed with the concept. Lavelle concluded that current evidence is insufficient to unequivocally support the premise that periodontal infections constitute an independent risk factor for coronary heart disease. Since the potential health impact of this relationship might be extensive, further studies are needed for re-examing the association between periodontal disease and coronary heart disease
CITATION STYLE
Wangsarahardja, K. (2005). Penyakit periodontal sebagai faktor risiko penyakit jantung koroner. Universa Medicina, 24(3), 136–144. Retrieved from http://www.univmed.org/wp-content/uploads/2011/02/Kartika(1).pdf
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